Drug profile

The FDA adverse-event record for Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp

Name: Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

403 FDA reports name Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#348 of 2,679
by report volume (all drugs): 403
adverse-event reports: 1.2%
death-coded share: Dog
most-reported species

Compiled by PlainBreed

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Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp ranks #348 of 2679 by total reports (403) and #1050 of 1130 by death-coded share (1.2%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #348
This drug, reports of 2679: #1050
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp has 403 reports now versus 403 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp changes

Signature read: 403 reports place Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp in the upper third of FDA AER volume (#348 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

403

Total Reports

Deaths Reported

1.2%

Death-coded share of reports

Active Ingredients

Betamethasone Valerate, UspClotrimazole, UspGentamicin Sulfate, Usp

Administration Routes

Auricular (Otic)UnknownTopicalIntradermalTransdermal

Species Affected

Dog 393

Cat 7

Unknown 3

Most Affected Breeds

Unknown 80

Retriever - Labrador 34

Terrier - Yorkshire 17

Chihuahua 14

Boxer (German Boxer) 12

Pug 12

Pit Bull 12

Terrier - West Highland White 11

Retriever - Golden 10

Shepherd Dog - German 9

Most Reported Reactions

Deafness 313

PR-EAR(S), LESION(S) 47

Partial deafness 17

Loss of hearing 16

Hearing affected 13

Hearing decreased 7

Temporary deafness 7

Impaired hearing 5

Vomiting 4

Anorexia 3

Skin irritation 3

Diarrhoea 2

Outcome Breakdown

Ongoing

202 (52.2%)

Outcome Unknown

125 (32.3%)

Recovered/Normal

48 (12.4%)

Recovered with Sequela

7 (1.8%)

Euthanized

3 (0.8%)

Died

2 (0.5%)

Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (403 here).

Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 400 Denamarin 400 Canine B Burgdorferi *2 Alu Kb 398 Canine Influenza Virus H3N8;Canine Influenza Virus H3N2 398

Similar death-coded share

Nearest other drugs by death-coded share (1.2% here), distinct from the volume row.

Altrenogest Oily Solution 1.2% Allergy Tablet (Unknown) 1.2% Orbifloxacin, Mometasone, Posaconazole 1.3% Ivermectin 68Mcg, Pyrantel Pamoate 57Mg, Praziquantel 57Mg 1.2%

What to do with this drug

Compare Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp's report volume and death-coded share against similar drugs nationwide. See similar drugs
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp (#348 of 2,679 by report volume); death-coded 1.2%. PlainBreed drug row · report volume stamp 403 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →