Drug profile

The FDA adverse-event record for Benazapril

73 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Benazapril. See the species affected, top reactions, and outcomes below.

73
adverse-event reports
17.8%
death-coded share
Dog
most-reported species
12
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
73
Total Reports
13
Deaths Reported
17.8%
Death Rate

Active Ingredients

Benazapril

Administration Routes

OralUnknownIntradermalTransdermal

Species Affected

Dog 66
Cat 7

Most Affected Breeds

Beagle 6
Crossbred Canine/dog 6
Retriever - Labrador 5
Schnauzer (unspecified) 4
Pinscher - Miniature 3
Spitz - German Pomeranian 3
Boxer (German Boxer) 3
Domestic Shorthair 3
Schnauzer - Miniature 2
Terrier - Jack Russell 2

Most Reported Reactions

Vomiting 12
Weight loss 11
Elevated blood urea nitrogen (BUN) 10
Diarrhoea 9
Death by euthanasia 9
Lethargy (see also Central nervous system depression in 'Neurological') 9
Other abnormal test result NOS 8
Hyperkalaemia 8
Dehydration 8
Decreased appetite 8
Not eating 8
Inappropriate urination 8

Outcome Breakdown

Outcome Unknown
27 (37.0%)
Ongoing
18 (24.7%)
Recovered/Normal
14 (19.2%)
Euthanized
9 (12.3%)
Died
4 (5.5%)
Recovered with Sequela
1 (1.4%)

Benazapril Adverse Event Insights

73 reports name Benazapril; 13 recorded a death outcome (17.8% of reported events, not a population-level mortality rate). Active ingredient: Benazapril. Administration routes: Oral, Unknown, Intradermal, Transdermal.

By species: Dog (66 reports), Cat (7 reports). By breed: Beagle (6), Crossbred Canine/dog (6), Retriever - Labrador (5).

Leading clinical signs: Vomiting (12), Weight loss (11), Elevated blood urea nitrogen (BUN) (10), Diarrhoea (9). Outcome, 73 coded reports: Outcome Unknown leads at 37.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.