Drug profile

The FDA adverse-event record for Baytril Otic

15 FDA reports name Baytril Otic, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2077 of 2,679
by report volume (all drugs)
15
adverse-event reports
20.0%
death-coded share
Dog
most-reported species
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Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Baytril Otic ranks #2072 of 2679 by total reports (15). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#2072
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Baytril Otic has 15 reports now versus 14 in that prior snapshot: 1 more (7.1%).

Report change
+1
Death-coded reports
+1
Death-coded share
+5.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Baytril Otic changes

Signature read: 15 reports place Baytril Otic in the lower third of FDA AER volume (#2077 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
3
Deaths Reported
20.0%
Death-coded share of reports

Active Ingredients

Baytril Otic

Administration Routes

Auricular (Otic)Unknown

Species Affected

Dog 14
Cat 1

Most Affected Breeds

Retriever - Labrador 6
Dog (unknown) 2
Shih Tzu 2
Ragdoll 1
Lhasa Apso 1
Poodle (unspecified) 1
Crossbred Canine/dog 1
Bulldog - French 1

Most Reported Reactions

Polyuria 5
Lethargy (see also Central nervous system depression in Neurological) 4
Not himself/herself 4
Polydipsia 4
Hypoalbuminaemia 3
Death by euthanasia 3
Falling 3
Intentional misuse 3
Diarrhoea 2
Bloody diarrhoea 2
Elevated total bilirubin 2
Hyperglycaemia 2

Outcome Breakdown

Ongoing
10 (66.7%)
Euthanized
3 (20.0%)
Outcome Unknown
1 (6.7%)
Recovered/Normal
1 (6.7%)

Baytril Otic: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Baytril Otic (#2077 of 2,679 by report volume); death-coded 20.0%. PlainBreed drug row · report volume stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →