Drug profile

The FDA adverse-event record for Bacitracin-Neomycin-Polymyxin

13 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bacitracin-Neomycin-Polymyxin. See the species affected, top reactions, and outcomes below.

13
adverse-event reports
15.4%
death-coded share
Dog
most-reported species
3
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
13
Total Reports
2
Deaths Reported
15.4%
Death Rate

Active Ingredients

Bacitracin-Neomycin-Polymyxin

Administration Routes

OphthalmicIntraocularUnknownTopical

Species Affected

Dog 11
Cat 2

Most Affected Breeds

Retriever - Labrador 4
Domestic Shorthair 2
Chihuahua 1
Terrier - Yorkshire 1
Terrier - Boston 1
Pinscher - Miniature 1
Terrier - West Highland White 1
Shih Tzu 1
Poodle (unspecified) 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 3
Elevated alanine aminotransferase (ALT) 3
Elevated serum alkaline phosphatase (SAP) 3
Vomiting 3
Corneal ulcer 3
Swelling around eye 2
Cough 2
Circling - neurological disorder (see also 'Behavioural disorders') 2
Elevated liver enzymes 2
Eyelid oedema 1
Eye disorder NOS (for photophobia see 'neurological') 1
Conjunctival oedema 1

Outcome Breakdown

Ongoing
7 (53.8%)
Recovered/Normal
3 (23.1%)
Died
2 (15.4%)
Outcome Unknown
1 (7.7%)

Bacitracin-Neomycin-Polymyxin Adverse Event Insights

13 reports name Bacitracin-Neomycin-Polymyxin; 2 recorded a death outcome (15.4% of reported events, not a population-level mortality rate). Active ingredient: Bacitracin-Neomycin-Polymyxin. Administration routes: Ophthalmic, Intraocular, Unknown, Topical.

By species: Dog (11 reports), Cat (2 reports). By breed: Retriever - Labrador (4), Domestic Shorthair (2), Chihuahua (1).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (3), Elevated alanine aminotransferase (ALT) (3), Elevated serum alkaline phosphatase (SAP) (3), Vomiting (3). Outcome, 13 coded reports: Ongoing leads at 53.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.