Drug profile

The FDA adverse-event record for Apomorphine

131 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Apomorphine. See the species affected, top reactions, and outcomes below.

131
adverse-event reports
8.4%
death-coded share
Dog
most-reported species
54
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
131
Total Reports
11
Deaths Reported
8.4%
Death Rate

Active Ingredients

Apomorphine

Administration Routes

UnknownIntravenousSubconjunctivalOphthalmicIntramuscularIntraocularOtherSubcutaneousParenteralUrethral

Species Affected

Dog 127
Cat 4

Most Affected Breeds

Retriever - Labrador 18
Dog (unknown) 8
Crossbred Canine/dog 8
Retriever - Golden 8
Beagle 6
Terrier - Yorkshire 4
Mixed (Dog) 3
Domestic Shorthair 3
Shih Tzu 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 3

Most Reported Reactions

Vomiting 54
Accidental exposure 33
Overdose 28
Seizure NOS 14
Lethargy (see also Central nervous system depression in 'Neurological') 13
Emesis 13
Tremor 8
Diarrhoea 7
Other abnormal test result NOS 7
Anorexia 7
Elevated blood urea nitrogen (BUN) 7
Death 6

Outcome Breakdown

Recovered/Normal
51 (38.9%)
Ongoing
42 (32.1%)
Outcome Unknown
27 (20.6%)
Died
6 (4.6%)
Euthanized
5 (3.8%)

Apomorphine Adverse Event Insights

131 reports name Apomorphine; 11 recorded a death outcome (8.4% of reported events, not a population-level mortality rate). Active ingredient: Apomorphine. Administration routes: Unknown, Intravenous, Subconjunctival, Ophthalmic.

By species: Dog (127 reports), Cat (4 reports). By breed: Retriever - Labrador (18), Dog (unknown) (8), Crossbred Canine/dog (8).

Leading clinical signs: Vomiting (54), Accidental exposure (33), Overdose (28), Seizure NOS (14). Outcome, 131 coded reports: Recovered/Normal leads at 38.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.