Drug profile

The FDA adverse-event record for Apomorphine

132 FDA reports name Apomorphine, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#677 of 2,679
by report volume (all drugs)
132
adverse-event reports
8.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Apomorphine ranks #676 of 2679 by total reports (132) and #626 of 1130 by death-coded share (8.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#676
This drug, reports of 2679
#626
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Apomorphine has 132 reports now versus 132 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Apomorphine changes

Signature read: 132 reports place Apomorphine in the upper third of FDA AER volume (#677 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
132
Total Reports
11
Deaths Reported
8.3%
Death-coded share of reports

Active Ingredients

Apomorphine

Administration Routes

UnknownIntravenousSubconjunctivalOphthalmicIntramuscularIntraocularOtherSubcutaneousParenteralUrethral

Species Affected

Dog 128
Cat 4

Most Affected Breeds

Retriever - Labrador 18
Crossbred Canine/dog 9
Dog (unknown) 8
Retriever - Golden 8
Beagle 6
Terrier - Yorkshire 4
Mixed (Dog) 3
Domestic Shorthair 3
Shih Tzu 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 3

Most Reported Reactions

Vomiting 54
Accidental exposure 33
Overdose 28
Seizure NOS 14
Lethargy (see also Central nervous system depression in 'Neurological') 13
Emesis 13
Tremor 9
Diarrhoea 7
Other abnormal test result NOS 7
Anorexia 7
Elevated blood urea nitrogen (BUN) 7
Ataxia 6

Outcome Breakdown

Recovered/Normal
51 (38.6%)
Ongoing
43 (32.6%)
Outcome Unknown
27 (20.5%)
Died
6 (4.5%)
Euthanized
5 (3.8%)

Apomorphine: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Apomorphine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (8.3% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Apomorphine (#677 of 2,679 by report volume); death-coded 8.3%. PlainBreed drug row · report volume stamp 132 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →