Amoxicillin, Clavulanate

1,386 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,386
Total Reports
82
Deaths Reported
590.0%
Death Rate

Active Ingredients

Amoxicillin, Clavulanate

Administration Routes

UnknownOralTopicalOphthalmic

Species Affected

Unknown 855
Dog 340
Cat 185
Human 5
Rat 1

Most Affected Breeds

Unknown 862
Domestic (unspecified) 136
Crossbred Canine/dog 46
Retriever - Labrador 28
Chihuahua 19
Cat (unknown) 18
Terrier - Yorkshire 16
Maltese 15
Dachshund (unspecified) 14
Spaniel - Cocker American 13

Most Reported Reactions

Color, Abnormal 771
Suspension, Abnormal 584
Vomiting 149
Anorexia 101
Depression 100
Seal, Abnormal 87
Lack of efficacy (bacteria) - NOS 82
Granules/Powder, Abnormal 58
Diarrhoea 52
Death 50
Elevated alanine aminotransferase (ALT) 37
Fever 33

Outcome Breakdown

Died
79 (84.9%)
Recovered/Normal
5 (5.4%)
Euthanized
3 (3.2%)
Outcome Unknown
3 (3.2%)
Ongoing
3 (3.2%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.