Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate)
1,076 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,076
Total Reports
130
Deaths Reported
1210.0%
Death Rate
Active Ingredients
Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate)
Administration Routes
OralUnknownSubcutaneousOphthalmicAuricular (Otic)Other
Species Affected
Dog 489
Unknown 395
Cat 191
Other 1
Most Affected Breeds
Unknown 396
Domestic Shorthair 112
Retriever - Labrador 47
Chihuahua 40
Shih Tzu 30
Terrier - Yorkshire 27
Domestic Longhair 24
Maltese 21
Retriever - Golden 19
Pug 19
Most Reported Reactions
Color, Abnormal 305
No sign 208
Vomiting 189
Lethargy (see also Central nervous system depression in 'Neurological') 153
Anorexia 113
Other abnormal test result NOS 86
Lack of efficacy (bacteria) - NOS 80
Uncoded sign 77
Diarrhoea 68
Death 63
Death by euthanasia 60
Elevated serum alkaline phosphatase (SAP) 58
Outcome Breakdown
Ongoing
352 (51.6%)
Recovered/Normal
107 (15.7%)
Outcome Unknown
93 (13.6%)
Died
69 (10.1%)
Euthanized
61 (8.9%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.