Drug profile

The FDA adverse-event record for Amoxicillin Anhydrous + Clavulanic Acid

38 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Amoxicillin Anhydrous + Clavulanic Acid. See the species affected, top reactions, and outcomes below.

38
adverse-event reports
15.8%
death-coded share
Unknown
most-reported species
9
Color, Abnormal - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
38
Total Reports
6
Deaths Reported
15.8%
Death Rate

Active Ingredients

Amoxicillin AnhydrousClavulanic Acid

Administration Routes

UnknownOral

Species Affected

Unknown 20
Dog 15
Cat 3

Most Affected Breeds

Unknown 20
Retriever - Golden 3
Dachshund (unspecified) 2
Crossbred Canine/dog 2
Pointing Dog - German Short-haired 1
Domestic Longhair 1
Boxer (German Boxer) 1
Bulldog 1
Retriever - Labrador 1
Griffon - French Wire-haired Pointing 1

Most Reported Reactions

Color, Abnormal 9
Death by euthanasia 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Vomiting 5
Suspension, Abnormal 4
Anaemia NOS 4
Diarrhoea 4
Abnormal ultrasound finding 4
Other abnormal test result NOS 4
Lot # and/or Expiration date incorrect 4
Contamination, Mold 4
Anorexia 3

Outcome Breakdown

Euthanized
5 (29.4%)
Recovered/Normal
4 (23.5%)
Outcome Unknown
3 (17.6%)
Ongoing
3 (17.6%)
Recovered with Sequela
1 (5.9%)
Died
1 (5.9%)

Amoxicillin Anhydrous + Clavulanic Acid Adverse Event Insights

38 reports name Amoxicillin Anhydrous + Clavulanic Acid; 6 recorded a death outcome (15.8% of reported events, not a population-level mortality rate). Active ingredients: Amoxicillin Anhydrous, Clavulanic Acid. Administration routes: Unknown, Oral.

By species: Unknown (20 reports), Dog (15 reports), Cat (3 reports). By breed: Unknown (20), Retriever - Golden (3), Dachshund (unspecified) (2).

Leading clinical signs: Color, Abnormal (9), Death by euthanasia (6), Lethargy (see also Central nervous system depression in 'Neurological') (5), Vomiting (5). Outcome, 17 coded reports: Euthanized leads at 29.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.