Amantadine
428 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
428
Total Reports
83
Deaths Reported
1940.0%
Death Rate
Active Ingredients
Amantadine
Administration Routes
UnknownOralSubcutaneous
Species Affected
Dog 426
Cat 2
Most Affected Breeds
Retriever - Labrador 86
Shepherd Dog - German 29
Crossbred Canine/dog 25
Retriever - Golden 25
Terrier - Bull - American Pit 18
Rottweiler 14
Boxer (German Boxer) 14
Mastiff (unspecified) 11
Dog (unknown) 10
Collie - Border 10
Most Reported Reactions
Death by euthanasia 60
Diarrhoea 47
Lethargy (see also Central nervous system depression in Neurological) 46
Vomiting 43
Ataxia 36
Lack of efficacy - NOS 35
Polydipsia 35
Limb weakness 35
Elevated alanine aminotransferase (ALT) 32
Partial lack of efficacy 32
Polyuria 31
Not eating 27
Outcome Breakdown
Ongoing
216 (50.5%)
Outcome Unknown
73 (17.1%)
Euthanized
59 (13.8%)
Recovered/Normal
56 (13.1%)
Died
24 (5.6%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.