Afoxolaner, Moxidectin, Pyrantel

10 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
10
Total Reports
4
Deaths Reported
4000.0%
Death Rate

Active Ingredients

Afoxolaner, Moxidectin, Pyrantel

Administration Routes

OralUnknown

Species Affected

Dog 10

Most Affected Breeds

Retriever - Labrador 5
Terrier - Bull - American Pit 2
Beagle 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Pointer (unspecified) 1

Most Reported Reactions

Elevated serum alkaline phosphatase (ALP) 5
Regurgitation 4
Lethargy (see also Central nervous system depression in Neurological) 4
Dull 4
Dehydration 4
Elevated amylase 4
Abnormal radiograph finding 4
Neutropenia 4
Inappetence 3
Nausea 3
Depression 3
Weakness 3

Outcome Breakdown

Ongoing
6 (60.0%)
Euthanized
3 (30.0%)
Died
1 (10.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.