Afoxolaner + Moxidectin + Pyrantel
72 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
72
Total Reports
6
Deaths Reported
830.0%
Death Rate
Active Ingredients
AfoxolanerAfoxolaner + Moxidectin + PyrantelMoxidectinPyrantel
Administration Routes
UnknownOral
Species Affected
Dog 70
Unknown 2
Most Affected Breeds
Retriever - Labrador 10
Retriever - Golden 5
Crossbred Canine/dog 5
Shepherd Dog - German 5
Dachshund (unspecified) 4
Chihuahua 4
Beagle 3
Shepherd Dog - Australian 3
Unknown 2
Hound (unspecified) 2
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 14
Other abnormal test result NOS 12
Lack of efficacy (endoparasite) - hookworm 10
Vomiting 10
Lethargy (see also Central nervous system depression in Neurological) 9
Diarrhoea 8
Not eating 7
Decreased appetite 6
Lack of efficacy (endoparasite) - tapeworm 6
Elevated serum alkaline phosphatase (ALP) 5
Lack of efficacy - NOS 4
Cough 4
Outcome Breakdown
Outcome Unknown
39 (55.7%)
Ongoing
18 (25.7%)
Recovered/Normal
7 (10.0%)
Died
5 (7.1%)
Euthanized
1 (1.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.