Afoxolaner + Milbemycin Oxime

22 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

0.0%

Death Rate

Active Ingredients

AfoxolanerAfoxolaner + Milbemycin OximeMilbemycin Oxime

Administration Routes

OralUnknown

Species Affected

Dog 22

Most Affected Breeds

Retriever - Labrador 3

Beagle 2

Bulldog - French 2

Pit Bull 2

Spitz - German Pomeranian 1

Unknown 1

Dog (unknown) 1

Retriever - Golden 1

Terrier - Jack Russell 1

Terrier (unspecified) 1

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 13

Abnormal ultrasound finding 3

Vomiting 3

Lethargy (see also Central nervous system depression in 'Neurological') 2

Elevated alanine aminotransferase (ALT) 2

Inappetence 1

Seizure NOS 1

Other abnormal test result NOS 1

Urinary tract infection 1

Bloody diarrhoea 1

Diarrhoea 1

Lack of efficacy - NOS 1

Outcome Breakdown

Outcome Unknown

14 (63.6%)

Ongoing

4 (18.2%)

Recovered with Sequela

2 (9.1%)

Recovered/Normal

2 (9.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.