Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet
2,159 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,159
Total Reports
31
Deaths Reported
140.0%
Death Rate
Active Ingredients
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet
Administration Routes
OralUnknownTopicalSubcutaneous
Species Affected
Dog 1,960
Unknown 198
Human 1
Most Affected Breeds
Retriever - Labrador 324
Unknown 199
Retriever - Golden 183
Crossbred Canine/dog 160
Pit Bull 119
Shepherd Dog - Australian 116
Shepherd Dog - German 100
Dog (unknown) 73
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 63
Collie - Border 53
Most Reported Reactions
Vomiting 303
Lack of efficacy (endoparasite) - heartworm 293
Lack of efficacy (endoparasite) - hookworm 245
Lack of efficacy (bacteria) - Borrelia 191
Tablets, Abnormal 181
Diarrhoea 167
Lack of efficacy (endoparasite) - roundworm NOS 147
Lethargy (see also Central nervous system depression in Neurological) 133
Lack of efficacy (endoparasite) - tapeworm 103
Seizure NOS 93
Lack of efficacy (ectoparasite) - flea 82
Lack of efficacy (ectoparasite) - tick NOS 67
Outcome Breakdown
Outcome Unknown
1,067 (54.4%)
Recovered/Normal
484 (24.7%)
Ongoing
379 (19.3%)
Died
17 (0.9%)
Euthanized
14 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.