Afoxolaner 37.5Mg / Moxidectin 180Mcg / Pyrantel 75Mg Chewable Tablet
1,348 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,348
Total Reports
21
Deaths Reported
160.0%
Death Rate
Active Ingredients
Afoxolaner 37.5Mg / Moxidectin 180Mcg / Pyrantel 75Mg Chewable Tablet
Administration Routes
OralUnknownTopicalPeriarticular
Species Affected
Dog 1,227
Unknown 116
Human 3
Cat 2
Most Affected Breeds
Unknown 119
Beagle 93
Retriever - Golden 88
Crossbred Canine/dog 68
Bulldog - French 67
Shepherd Dog - Australian 57
Dog (unknown) 54
Shih Tzu 48
Retriever - Labrador 46
Spaniel - King Charles Cavalier 45
Most Reported Reactions
Vomiting 313
Diarrhoea 150
Lack of efficacy (endoparasite) - hookworm 146
Lethargy (see also Central nervous system depression in Neurological) 126
Tablets, Abnormal 109
Lack of efficacy (endoparasite) - roundworm NOS 105
Lack of efficacy (bacteria) - Borrelia 90
Lack of efficacy (endoparasite) - heartworm 68
Seizure NOS 60
Lack of efficacy (ectoparasite) - flea 56
Itching 43
Lack of efficacy (endoparasite) - tapeworm 39
Outcome Breakdown
Outcome Unknown
626 (50.8%)
Recovered/Normal
416 (33.7%)
Ongoing
170 (13.8%)
Died
12 (1.0%)
Euthanized
9 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.