Afoxolaner 2.27% Chewable Tablet (68 Mg)
272 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
272
Total Reports
8
Deaths Reported
290.0%
Death Rate
Active Ingredients
Afoxolaner 2.27% Chewable Tablet (68 Mg)
Administration Routes
OralUnknown
Species Affected
Dog 272
Most Affected Breeds
Crossbred Canine/dog 35
Dog (unknown) 23
Collie - Border 17
Spaniel - Cocker American 15
Retriever - Golden 12
Retriever - Labrador 11
Shepherd Dog - German 8
Bulldog - French 8
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 6
Spaniel - Cocker English 6
Most Reported Reactions
Vomiting 71
Skin disorders NOS 45
Pruritus 43
Diarrhoea 30
Lack of efficacy (ectoparasite) - tick NOS 27
Lack of efficacy (ectoparasite) - flea 24
Lethargy (see also Central nervous system depression in 'Neurological') 19
Erythema (for urticaria see Immune SOC) 15
Anorexia 14
Panting 11
Seizure NOS 11
Scratching 11
Outcome Breakdown
Recovered/Normal
136 (50.0%)
Outcome Unknown
109 (40.1%)
Ongoing
19 (7.0%)
Died
5 (1.8%)
Euthanized
3 (1.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.