Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet
1,747 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,747
Total Reports
34
Deaths Reported
190.0%
Death Rate
Active Ingredients
Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet
Administration Routes
OralUnknownParenteralPerineural
Species Affected
Dog 1,556
Unknown 191
Most Affected Breeds
Retriever - Labrador 348
Shepherd Dog - German 196
Unknown 191
Retriever - Golden 180
Dog (unknown) 134
Pit Bull 66
Great Pyrenees 51
Crossbred Canine/dog 51
Mountain Dog - Bernese 46
Boxer (German Boxer) 40
Most Reported Reactions
Vomiting 273
Lack of efficacy (endoparasite) - heartworm 209
Tablets, Abnormal 193
Diarrhoea 148
Lack of efficacy (bacteria) - Borrelia 146
Lethargy (see also Central nervous system depression in Neurological) 136
Lack of efficacy (endoparasite) - hookworm 121
Seizure NOS 95
Lack of efficacy (endoparasite) - tapeworm 85
Lack of efficacy (endoparasite) - roundworm NOS 77
Itching 69
Lack of efficacy (bacteria) - Anaplasma 62
Outcome Breakdown
Outcome Unknown
858 (55.1%)
Recovered/Normal
399 (25.6%)
Ongoing
265 (17.0%)
Died
21 (1.3%)
Euthanized
13 (0.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.