Advantage Multi

58 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

520.0%

Death Rate

Active Ingredients

Advantage Multi

Administration Routes

TopicalUnknownOral

Species Affected

Dog 54

Cat 4

Most Affected Breeds

Retriever - Labrador 6

Chihuahua 5

Crossbred Canine/dog 4

Boxer (German Boxer) 2

Siberian Husky 2

Black Mouth Cur 2

Terrier (unspecified) 2

Retriever - Golden 2

Shepherd Dog - Australian 2

Greyhound 2

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 41

Overdose 4

Decreased appetite 4

Elevated total bilirubin 4

Weight loss 4

Anaemia NOS 3

Neutropenia 3

Lymphopenia 3

Hypoproteinaemia 3

Anxiety 2

Other abnormal test result NOS 2

Drug dose administration interval too long 2

Outcome Breakdown

Ongoing

41 (70.7%)

Outcome Unknown

13 (22.4%)

Died

2 (3.4%)

Euthanized

1 (1.7%)

Recovered/Normal

1 (1.7%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.