Drug profile

The FDA adverse-event record for Acetylcysteine Solution

17 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Acetylcysteine Solution. See the species affected, top reactions, and outcomes below.

17
adverse-event reports
64.7%
death-coded share
Dog
most-reported species
11
Elevated alanine aminotransferase (ALT) - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
17
Total Reports
11
Deaths Reported
64.7%
Death Rate

Active Ingredients

Acetylcysteine Solution

Administration Routes

UnknownIntravenous

Species Affected

Dog 17

Most Affected Breeds

Retriever - Labrador 9
Shar Pei 1
Mixed (Dog) 1
Beagle 1
Spaniel - Cocker American 1
Terrier - Bull - American Pit 1
Dachshund - Miniature 1
Schnauzer - Miniature 1
Bulldog - French 1

Most Reported Reactions

Elevated alanine aminotransferase (ALT) 11
Elevated total bilirubin 10
Vomiting 9
Elevated serum alkaline phosphatase (SAP) 9
Elevated liver enzymes 8
Anorexia 7
Other abnormal test result NOS 7
Abnormal ultrasound finding 7
Lethargy (see also Central nervous system depression in 'Neurological') 7
Leucocytosis NOS 6
Death by euthanasia 6
Anaemia NOS 5

Outcome Breakdown

Euthanized
6 (35.3%)
Died
5 (29.4%)
Ongoing
5 (29.4%)
Recovered/Normal
1 (5.9%)

Acetylcysteine Solution Adverse Event Insights

17 reports name Acetylcysteine Solution; 11 recorded a death outcome (64.7% of reported events, not a population-level mortality rate). Active ingredient: Acetylcysteine Solution. Administration routes: Unknown, Intravenous.

By species: Dog (17 reports). By breed: Retriever - Labrador (9), Shar Pei (1), Mixed (Dog) (1).

Leading clinical signs: Elevated alanine aminotransferase (ALT) (11), Elevated total bilirubin (10), Vomiting (9), Elevated serum alkaline phosphatase (SAP) (9). Outcome, 17 coded reports: Euthanized leads at 35.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.