Drug profile

The FDA adverse-event record for Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine

48 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine. Species, reactions, and outcomes follow.

#1140 of 2,679
by report volume (all drugs)
48
adverse-event reports
2.1%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine ranks #1140 of 2679 by total reports (48). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1140
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine has 48 reports now versus 48 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine changes

Signature read: Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine's 2.1% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
48
Total Reports
1
Deaths Reported
2.1%
Death-coded share of reports

Active Ingredients

Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine

Administration Routes

Auricular (Otic)UnknownIntraocular

Species Affected

Dog 48

Most Affected Breeds

Retriever - Labrador 7
Terrier - Yorkshire 5
Spaniel - Cocker American 4
Terrier - Jack Russell 3
Pug 3
Maltese 3
Pinscher - Miniature 2
Dachshund (unspecified) 2
Shepherd Dog - Australian 2
Poodle - Miniature 2

Most Reported Reactions

Lack of efficacy - NOS 24
Deafness 4
Impaired hearing 4
Loss of hearing 4
Vomiting 3
CULTURE/TITER DATA ABNORMAL 3
Head shake - ear disorder 3
Other abnormal test result NOS 3
Ear discharge 3
Elevated temperature 2
Behavioural disorder NOS 2
Lethargy (see also Central nervous system depression in 'Neurological') 2

Outcome Breakdown

Outcome Unknown
26 (54.2%)
Ongoing
16 (33.3%)
Recovered/Normal
4 (8.3%)
Euthanized
1 (2.1%)
Recovered with Sequela
1 (2.1%)

Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Acetic Acid + Boric Acid + Glycerin + Polysorbate + Triethanolamine (#1140 of 2,679 by report volume); death-coded 2.1%. PlainBreed drug row · death-coded share stamp 2.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →